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Issue 10-2
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IGR 10-2
Telling someone they have a disease will itself cause a loss of quality of life
A higher intake of certain fruits and vegetables (green collards and kale, carrots, peaches) in older women may be associated with a decreased risk of glaucoma
Frizzled-related protein-1 (sFRP-1), is elevated in trabecular meshwork cells from eyes with glaucoma
There needs be a case by case determination about cessation of anticoagulation before undergoing glaucoma surgery
Glial cell changes observed in the primate LGN support the role of glia in central visual system neurodegeneration and remodelling in glaucoma
Have we been looking at the wrong side of the optic nerve in primary open-angle glaucoma?
There is an association between poor functional health literacy and worse glaucoma outcomes
When our patients ask us about caffeine intake and glaucoma, we should tell them that caffeine was not associated with glaucoma
Tubes can have a fairly good success rate in some types of pediatric glaucoma
Outflow resistance is not a major player in setting up the nighttime IOP
Annual US patient costs for POAG are higher than the gross national income of 77 countries
Transconjunctival sutures are a practical, less invasive corrective procedure for the treatment of hypotony maculopathy associated with overfiltration
In the near future, whole genome association(WGA) in primary glaucoma's with densely linked single nucleotide polymorphisms (SNPs) covering the entire genome on high throughput micro array platforms would be the method of choice
Axon damage precedes RGC dendrite and soma changes in the DBA/2J mouse
BDNF preserved the fine dendritic architecture of surviving RGCs after optic nerve crush injury
At the present time, there is no Oxford Level I evidence that short-term or long-term IOP fluctuation or variation is an independent risk factor for glaucoma progression
Patients receiving preserved levobunolol had conjunctival changes, with decreased goblet cells and increased cellular abnormalities compared to unpreserved levobunolol treated patients
Latanoprost-treated irises darken because of an increased amount of melanin within the melanocytes particularly those of the anterior border region of the iris stroma
Event analyses generally identify progression sooner than trend analyses
Only three genes, namely MYOC,13 optineurin (OPTN)14 and WDR3615 have been characterized, that harbor disease-associated mutations with high degrees of allelic heterogeneity in different populations
The lack of identification of all the genes involved at various stages of glaucoma pathophysiology has restricted the understanding of gene-gene interactions as well as genotype-phenotype correlation in glaucoma
Patient-centered outcomes should drive clinicians' management of glaucoma
Spontaneous IOP fluctuations may be similar between fellow eyes during the same time period, but vary from day to day within eyes
Serum auto-antibodies, apart from being of potential pathogenic importance, may also serve as biomarkers of the disease
The current efficacy of SLT-360°-100, and ALT-180°-50 is superior over SLT delivered in overlapping spots over 180 degrees (SLT-180°-100)
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