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Issue 11-1
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News Flashes
IGR 11-1
We may be using the wrong visual tests for granting driving licenses
Human glaucoma patients with severe bilateral loss of retinal ganglion cells have the potential to suffer circadian rhythm disturbances
Glaucoma is a twenty-four-hour disease and agents which only lower IOP for part of this period are less than optimal glaucoma therapeutic options
Clinicians should have a protocol in the office to regularly verify calibration of their Goldmann tonometers
A logical inference is that defining change solely on the basis of an unsatisfactory reference standard, given that additional data is provided by other methods, should be abandoned
Numerous population-based studies continue to link ocular perfusion pressure to the presence, incidence and progression of glaucoma
Surgical devices and techniques targeting the drainage angle are on the rise
It is unclear how a neuroprotective effect of systemically administered brimonidine could be mediated
Phacoemulsification will provide a good visual outcome and control of IOP, particularly for the patients with angle-closure glaucoma and co-existing cataract
Drug delivery system (DDS) with artificial vitreous body and obtaining pluripotentcells from somatic cells by reprogramming are major steps forward towards our dream of effective neuroprotection and transplantation therapy
Will blocking mutant myocilin secretion be of therapeutic benefit?
Some, but not all, high responders to IVTA can be identified simply in advance using topical dexamethasone 4 times daily for a month
There is a need for untreated control groups in prospective studies evaluating any treatment modalities
RNFL thicknesses displayed on imaging system reports are approximate estimates and their value resides essentially in comparisons to individual or population-based values obtained with the same instrument
The lamina cribrosa, previously clinically unapproachable, may now be considered a diagnostic target for glaucoma
For the OCT the primary source of variability was the measurement of disc area
The reference plane height was the critical component of variability for parameter measurements for the CSLO
A double hump sign in identation gonioscopyis pathognomic for plateau iris
The retrograde transport of fluorogold at 23-28 days after nerve crush is used to measure the subset of RGCs that are still connected to the superior colliculus
Human trials of optic neuropathies, separating the neuroprotective effects seenin animals from IOP-reduction effects, will continue to challenge the study of bri-monidine
The outcome measure is a measure of dynein-mediated active axonal transport,which is the basis for fluorogold movement from the colliculus to the retina
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