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Issue 12-3
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IGR 12-3
Can amacrine cells be a ready source of ganglion cell replacement?
Ciliary sulcus tube insertion in eyes at risk for corneal decompensation
Transscleral diode laser cycloablation in patients with good vision as an alternative to standard surgical approaches
Efforts to move away from the quantitative, but poorly valid C/D method are needed
OHT and OHT with pigment dyspersion differ in location of outflow obstruction
Not only are we uncertain about the optimal number and timing of IOP measurements necessary to characterize circadian IOP - we may also have to accept uncertainty about the optimal tonometer choice for the task
The potential effect of antihypertensive effect on OAG risk may be different depending on the blood pressure level
Maximal IOP lowering with PGAs can be seen as early as one week
Bleb morphology is an important secondary measure of success, particularly as it may impact potentially vision threatening complications such as infection and hypotony
Although Mitomycin C improves post-trabeculectomy IOP control significantly, it also has an unpleasant habit of amplifying any imperfections in surgical technique
Ciliary sulcus placement of a glaucoma tube shunt in high risk eyes reduces the risk for corneal decompensation
At the moment there is no evidence for whether glaucoma screening is cost-effective or not
Retinal nerve fiber layer defects on color fundus photographs can be detected by a new computerized method
Success rates for biogradable implant and mitomycin-C are different
Water drinking increases axial length
Environmental co-factors or other genes, either alone or in conjunction with LOXL1, are permissive for the PXFG phenotype
High throughput genotyping reveals common genetic loci associated with optic disc area and vertical cup-disc ratio
In the posterior sclera of monkey eyes the collagen fibers are oriented circumferentially forming a ring around the scleral canal
Recently, trials of continuous IOP monitoring with a wireless ocular telemetry sensor have shown consistently higher nocturnal IOPs in glaucoma patients
Even a single diurnal IOP testing session may not be feasible in every clinical setting
Clinicians are largely ignoring the huge amount of data that is obtained with spectral domain OCT
Obtaining high-quality scans is a prerequisite for interpretation of retinal nerve fiber layer, optic disc and macular measurements obtained with optical coherence tomography
Scanning laser Doppler flowmetry has 'limited reproducibility' and 'is not capable of providing absolute blood flow values'
Phaco/IOL may be a reasonable and important part of the treatment armamentarium for treating ocular hypertension and for lowering the IOP in certain glaucoma patients
Despite some very promising animal work, the Ologen implant instead of MMC isn't part of the answer we are looking for
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