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Issue 22-3
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IGR 22-3
One finding which may be noteworthy is a 28-day lag in adherence decline after declaration of the crisis. Ophthalmologists may take advantage of this prime time to set up telemedicine systems and expand the capacity of mail delivery of medicine to home or neighborhood pharmacies
These data provide support for the benefit of our current treatment paradigms in delaying visual impairment from glaucoma
Although it is to be welcomed that impact in terms of severity of VI appears to be reducing in Finland and globally, this is tempered by the increasing numbers of glaucoma patients on account of the ageing of our populations
The authors found one positive result after studying a number of cognitive tests and thus the possibility of a false positive result are relatively high
While patients express their symptoms based on their experience from both eyes the models in this study utilizes data (visual field and nerve fiber thickness) from the worse eye
While the work is instructive about the molecular pathways involved in cell death and axon degeneration in glaucoma, it is unlikely that Bcl-xL, a potent oncogene, could ever be developed for human use
The WDT and DTC should not be considered diagnostic tests but risk assessment tests. Glaucoma is an optic nerve neuropathy, and IOP elevation above a pre-determined level is not a diagnostic criterion
The study demonstrates the potential of the EYEMATE-SC as a new device to fill the unmet need for continuous IOP monitoring
These findings confirm that there is presently no consensus on a single procedure that is optimal for determining glaucomatous visual field progression. Rather than regarding this as a problem it is helpful to regard this as an opportunity for new investigators to pursue
It seems likely that false positive findings in the current paper were artifactually high for the simple reason that early glaucomatous field loss frequently is associated with MD values that are not statistically outside normal limits, even at p<10%
Although alternative light sources may allow automated perimeters to achieve higher intensities, this may create undesirable effects due to scattered light and possible transient adaptation changes
The inclusion of SS-PERG amplitude adaptation improved detection of glaucomatous RGC dysfunction compared to SS-PERG amplitude alone
Translation of hemodynamic biomarkers into improved clinical care remains challenging due to limited longitudinal data linking them to structural and functional glaucoma progression
Capillary density measurements had higher diagnostic accuracies than RNFL thickness in detecting preperimetric glaucoma and early glaucoma
Their findings justify that OCTA and OCT complement each other in the diagnosis of early glaucoma
Deep macular vessel density, especially nasal grid, may be a promising structural parameter in severe glaucoma
Although a cause and effect relationship between niacin intake and glaucoma cannot be established from this observational study, it makes an important contribution in laying the foundation for performing future epidemiological cohort studies
George
et al.
carried out a prospective cohort study on 4302 participants of the rural and urban South Indian population (Chennai Eye Disease Incidence Study) to determine the association of metformin usage among subjects with diabetes mellitus and the six year incidence of POAG
Switching patients with PAPS from PGA treatment to OMDI result in improvement in PAPS symptom
The question remains whether short-term effects will simply revert or possibly contribute to long-term preservation of visual function
"Both studies failed to identify or to fully confirm these ""predictors"" due to the low event rates"
Topical anti-inflammatories may not be necessary following SLT
The benefit of these devices in a general glaucoma population remains to be clarified
Using drop application as a surrogate parameter for success can be considered less reliable than IOP measurement
The results up to 24 months suggest no clear advantages of one choice versus the other in terms of quality-of-life and cost-benefit ratio
Primary trabeculectomy is a viable option for a newly diagnosed advanced glaucoma population
By omitting measurements from 12am to 8am in the study protocol, valuable data have been missed, potentially underestimating true IOP range, hence fluctuation3
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