News Flashes (IGR: 24-4) | International Glaucoma Review #

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News Flashes IGR 24-4

The sequence of damage remains unknown for now: whether distal AHO pathway changes are due to primary dysgenesis of the vessels or high IOP vessel collapse from lack of flow that subsequently could be rescued later

Their results shine a powerful spotlight on the innovation and utility of modulating intracellular astrocyte signalling cascades using gene therapy for patient-specific interventions tailored to key points in progression

Little is known about dynamic IOP differences in the anterior and posterior chambers of the eye

Glaucoma induced higher IOP in the vitreous chamber than in the anterior chamber

Shorter tests mean less time to “listen” for false responses, leading to inaccurate— and often inflated—estimates of FPs

It is slightly disappointing to find that the results of this most recent study by Parakkel et al. reaffirm that, despite significant technological development, the diagnostic performance of PS-OCT remains similar to OCT-based RNFL thickness measures

Advances are underway for polarimetric imaging in glaucoma

Identification of shorter AL as a risk factor for NTG progression

There was a significant effort by the authors to control for potential confounders, which makes it an important addition to a body of evidence

Despite high rates of conjunctival hyperemia, ROCK inhibitors are an important addition to the glaucoma treatment armamentarium

Does reducing IOP variability decrease the rate of structural glaucoma progression?

The study did not include nighttime/ early morning IOP measurements, which could provide valuable insights into the relationship between nocturnal IOP fluctuations and glaucoma progression

PPA area can be a useful indicator of glaucoma progression

Issue 24-4

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