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Issue 24-4
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IGR 24-4
The sequence of damage remains unknown for now: whether distal AHO pathway changes are due to primary dysgenesis of the vessels or high IOP vessel collapse from lack of flow that subsequently could be rescued later
Their results shine a powerful spotlight on the innovation and utility of modulating intracellular astrocyte signalling cascades using gene therapy for patient-specific interventions tailored to key points in progression
Little is known about dynamic IOP differences in the anterior and posterior chambers of the eye
Glaucoma induced higher IOP in the vitreous chamber than in the anterior chamber
Shorter tests mean less time to “listen” for false responses, leading to inaccurate— and often inflated—estimates of FPs
It is slightly disappointing to find that the results of this most recent study by Parakkel et al. reaffirm that, despite significant technological development, the diagnostic performance of PS-OCT remains similar to OCT-based RNFL thickness measures
Advances are underway for polarimetric imaging in glaucoma
Identification of shorter AL as a risk factor for NTG progression
There was a significant effort by the authors to control for potential confounders, which makes it an important addition to a body of evidence
Despite high rates of conjunctival hyperemia, ROCK inhibitors are an important addition to the glaucoma treatment armamentarium
Does reducing IOP variability decrease the rate of structural glaucoma progression?
The study did not include nighttime/ early morning IOP measurements, which could provide valuable insights into the relationship between nocturnal IOP fluctuations and glaucoma progression
PPA area can be a useful indicator of glaucoma progression
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