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Issue 7-1
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IGR 7-1
OCT measurements of the anterior chamber angle give results similar to those obtained with conventional gonioscopy
Subclinical uveal effusion was demonstrated in 58% of acute and 20% of chronic PACG eyes, compared to 1.3% of open angle controls
All measures of visual field restriction were significantly correlated with accident frequency in glaucoma patients
There was no statistically significant relationship between central corneal thickness and axial length
Pseudoexfoliation is a major risk factor for the development of glaucoma
Mean central corneal thickness (CCT) of 616.6 ±108.3 micrometres and mean central lamina cribrosa thickness (LCT) 378.1 ±117.8 micrometres were statistically independent of each other
Therapy for ocular hypertensives is complicated by inadequate compliance, side-effects, and failure to take effect of quality of life into account (ARVO-Quigley)
Using previously obtained patient, rather than population derived, probability density functions can lead to a 30-60% saving in test timein perimetry without increasing error (ARVO-Chauhan)
Neuroprotection means permanent long term cell survival and not only anextension of cell survival for days or weeks (ARVO-Boehm)
Decreased blood pressure increased the likelihood of glaucomatous neurodegeneration in DBA/2J mice (ARVO-Boehm)
High-speed ultrahigh resolution OCT allows images of the living retina with a resolution less than 5 µm providing unprecedented non-invasive imaging of retinal morphology and physiology (ARVO-Aung / Boehm)
Scleral biomechanical properties are a major determinant of optic nerve head biomechanics (ARVO-Boehm)
Regulation of aqueous humor outflow in the trabecular meshwork and uveoscleral pathways may in fact be governed locally by proteins or enzymes made in the ciliary epithelium
Not a single subject with a mean eye pressure less than 14 mmHg progressed during the follow-up period after trabeculectomy with 5-fluorouracil (ARVO-Martin)
The cost of saving one eye from blindness by the treatment of ocular hypertension was estimated at $ 800,000 (ARVO-Quigley)
Oxidative stress may be a major factor contributing to the cellular changes that occur in the glaucomatous lateral geniculate nucleus
Statistical image mapping is a novel and exciting technique for detecting optic disc change in glaucoma (ARVO-Chauhan)
Caution against 'sequence bias' should be exercised by the examining clinician when judging longitudinal optic disc photography
Optical coherence tomography of the anterior segment can provide meaningful information regarding angle anatomy in a non-invasive (non-contact) fashion (AGS)
Elevated IOP may increase levels of endothelin
Stiffness of the peripapillary sclera in early glaucoma eyes was increased compared to peripapillary scleral stiffness in control eyes
Serum immunoreactivity in POAG is different from normals
ECM effects of TGF-β2 on ONH astrocytes are mediated by CTGF in vitro
Glatiramer acetate was not protective against retinal ganglion cell death
Bunazosin appears to protect the retina and optic nerve against the ischemic effect of endothelin-1
IOP was found to decrease with age in Japanese
There was no association between central corneal thickness and the risk for progression
Intraoperative OCT is feasible
In the European Glaucoma Prevention Study no difference was found between dorzolamide and placebo in treating OHT. Both reduced IOP!
Diurnal variations are less with latanoprost than with brimonidine
Polymorphisms in the Interleukin-1 gene (IL-1β +3953T) may protect an individual against developing POAG; results replicated in both American and Indian cohorts (ARVO-Aung)
Time-course of single cell apoptosis in vivo using video and image analysis of retinal ganglion cell disease model was demonstrated (ARVO-Aung)
CAT-152, an anti-TGF-β2 antibody used as a wound healing modulator, was shown not to have a significant advantage over placebo in a multicentre study of patients undergoing first-time trabeculectomy. These results were in contrast to previous positive results (ARVO-Chauhan)
A new valved seton was shown to reduce IOP in rabbit eyes with user defined pressure control (ARVO-Chauhan)
Dendritic pathology of lateral geniculate neurons in the brain occurs even if no significant optic nerve fiber damage is detectable (ARVO-Boehm)
Properties of the cornea other than its thickness, such as corneal hysteresis, may be independent predictors of glaucoma progression. Although significant in the univariate model, this association was less prominent in the multivariate model and requires further investigation (AGS)
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