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Issue 9-4
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News Flashes
IGR 9-4
The evidence for a role of vascular factors in glaucoma is mounting
Fear of glaucoma blindness is reduced over time
The use of biodegradable microspheres holds promise for the sustained delivery of biological therapeutic molecules like GDNF
At the most clinically significant calibration level of 20 mmHg, 32% of tonometers were outside of the manufacturer's specified tolerance
IOP variation between patient visits as a risk factor for glaucoma progression is important
Calcium channel blockers are associated with an increased risk of incident glaucoma
Increased intraocular temperature during laser iridotomy may cause bullous keratopathy
An exposed Ex-PRESS aqueous shunts can be removed through an adjacent new track
MMPs are integral in shaping the course of cellular events that ensue after ocular wounding
Obese children are not necessarily at higher risk for glaucoma during their lifetime
RNFL split bundles: a true anatomic variant and not just an artefact of imaging methods
Penetrating keratoplasty due to argon laser iridotomy- induced bullous keratopathy
Younger age, white race, lower education and lower income are associated with increased fear of blindness related to glaucoma
Remodeling of the lamina cribrosa and peripapillary sclera in monkey experimental glaucoma is a response to increased IOP
The relationship between the eye's biomechanical response and glaucomatous damage is not straightforward
The Scanning Peripheral Anterior Chamber Depth Analyzer identifies cases needing further detailed examination such as gonioscopy
GDxECC demonstrates advantages over GDx VCC
Evaluation through gap analysis provides information when a patient refills prescriptions, how long and frequent are therapy gaps and how long the total time off therapy
Glial cell line Derived Neurotrophic Factor treatment has the ability to abrogate both retinal and optic nerve pathology
With different time courses of gene expression, optic nerve transection and ocular hypertension models are not comparable, even though they share a few gene expressions
Prelaminar tissue volume and thickness increase in early glaucoma
The loss of ganglion cells (and their axons) is accompanied from the very start of disease by a loss of visual function
Preserved drugs quickly stimulate stress-induced signals in the ocular surface epithelia
Adherence suffers when patients are prescribed multiple medications
Before embracing the Ex-Press shunt there needs to be a better grasp of the long-term efficacy and complications of the procedure
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