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Abstract #127927 Published in IGR 25-3
Latin American Prevalence of Glaucoma: A Systematic Review and Meta-Analysis
Mora-Paez DJ; Guedes J; Amaral DC; Ferreira MA; Fernandes BF; Pereira SF; Botton B; Desai A; Pakter HM; Lavinsky F; Filho AACVision (Basel, Switzerland) 2025; 9:
We conducted a systematic review and meta-analysis to estimate the prevalence of all types of glaucoma in Latin America (LATAM) and evaluate potential demographic associations. This study followed PRISMA guidelines and was registered in PROSPERO (CRD42024506330). A comprehensive search of PubMed, SciELO, and Web of Science was conducted to identify population-based or cross-sectional studies reporting glaucoma prevalence in LATAM. Studies were categorized into two groups: Group 1 included general population studies without selection based on visual acuity (VA), and Group 2 included studies limited to individuals with VA < 20/60. Data from five studies in Group 1 (25,288 individuals) and eight studies in Group 2 (29,882 individuals) were analyzed using R software. The pooled prevalence of glaucoma was 4% (95% CI: 1-3%) in Group 1 and 1% (95% CI: 0-1%) in Group 2. No statistically significant associations were found between glaucoma prevalence and sex ( = 0.08) or age ( = 0.5669). Although our findings highlight the relevance of glaucoma as a public health concern in LATAM, the limited number of available studies and methodological variability reduce the certainty of the estimates.
Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA 19107, USA.
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