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Abstract #128046 Published in IGR 25-3

3-year real-world outcomes of standalone PreserFlo MicroShunt implantation - effectiveness and safety profile

PURPOSE: To report the three-year clinical outcomes and safety profile of standalone PreserFlo MicroShunt implantation. METHODS: A single-center, retrospective study of 151 eyes from 109 patients with open-angle glaucoma who underwent standalone microshunt implantation between February 2019 and December 2020. RESULTS: The mean IOP decreased significantly from 22.64 ± 8.79mmHg preoperatively to 12.76 ± 3.93mmHg three years postoperatively, with a mean IOP reduction of 43.6% (p = < 0.001). The need for IOP-lowering medication was significantly reduced from 2.64 ± 1.15 at baseline to 0.71 ± 1.12 after three years, representing a mean reduction of 73.1% (p = < 0.001). Three years post-implantation, 64.41% of eyes were free of glaucoma medication. Qualified and complete surgical success (IOP ≤ 21mmHg) was achieved in 77.6% and 42.3% of eyes, respectively, at three years. The most common complications were transient ocular hypotony (40.4%), choroidal detachment (13.25%), hyphema (11.92%). The vast majority of complications were self-limiting and did not pose a threat to vision. Open revision surgery was necessary in 14 eyes (9.27%). 7 eyes (4.63%) underwent further glaucoma surgery due to surgical failure. No statistically significant reduction in endothelial cell density (ECD) was observed 3 years after microshunt implantation (n = 13; p = 0.526). CONCLUSION: PreserFlo MicroShunt implantation is an effective surgical technique for lowering intraocular pressure and reducing the need for antiglaucoma medication while maintaining a favorable safety profile. Its effect remains stable three years after surgery.

Department of Ophthalmology, St. Johannes Hospital Dortmund, Johannesstrasse 9-17, 44137, Dortmund, Germany. ad.skowronski92@gmail.com.

Classification:

15 Miscellaneous

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