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Abstract #21194 Published in IGR 10-2
Travoprost/timolol fixed combination
Herceg M; Noecker RExpert Opinion in Pharmacotherapy 2008; 9: 1059-1065
BACKGROUND: Travoprost and timolol are topical ocular hypotensive medications that have been used in the treatment of glaucoma. The fixed combination eye drop, Duotrav (travoprost 0.004% and timolol maleate 0.5%), has recently been introduced into the market. OBJECTIVE: In this paper, the results of clinical trials and existing data on the performance of travoprost/timolol are discussed and analyzed. METHODS: Appropriate studies for review were identified using PubMed. Studies selected for review compared efficacy and side-effect profile of fixed combination travoprost/timolol with travoprost and timolol used concomitantly, latanoprost and timolol used concomitantly, fixed combination latanoprost/timolol, travoprost alone and timolol alone. RESULTS/CONCLUSION: Fixed combination eye drops such as travoprost/ timolol offer the potential benefits of increased patient adherence, reduced exposure to preservatives, and reduced cost.
Dr. R. Noecker, University of Pittsburgh School of Medicine, UPMC Eye Center, 203 Lothrop Street, Pittsburgh, PA 15213, USA
Classification:
11.13.4 Betablocker and prostaglandin (Part of: 11 Medical treatment > 11.13 Combination therapy)
