advertisement
Abstract #28226 Published in IGR 13-1
Advances in the understanding of ocular blood flow in glaucoma
Shoshani YZ; Harris A; Siesky BAExpert Review of Ophthalmology 2010; 5: 189-200
Although intraocular pressure remains the only current treatable risk factor in open-angle glaucoma, several other risk factors have been reported, including insufficient ocular blood flow and low perfusion pressure. Over the past several decades, significant progress has been made in the methodologies utilized to assess ocular blood flow as well as consensus in interpreting their results. Utilizing these devices, dozens of prospective investigations have revealed altered ocular blood flow, ocular perfusion pressure and faulty vascular regulation in patients with open-angle glaucoma. Pilot research studies have found reductions in ocular circulation to be associated with various markers of structural and functional glaucoma progression. However, these pilot studies have been limited in size, scope and execution, and only larger, multicentered prospective controlled studies are capable of providing definitive proof of the vascular role in glaucoma progression.
A. Harris. Glaucoma Research and Diagnostics Center, Indiana University School of Medicine, Department of Ophthalmology, 702 Rotary Circle, Indianapolis, IN 46202, United States. bsiesky@indiana.edu
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
