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Abstract #46105 Published in IGR 13-2
Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast spain: Determination and relationships
Garcia-Medina M; Garcia-Medina JJ; Garrido-Fernandez P; Galvan-Espinosa J; Martin-Molina J; Garcia-Maturana C; Perez-Pardo S; Pinazo-Duran MDClinical Ophthalmology 2011; 5: 249-258
Objective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region. Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher's asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe's robust test for each variable (IOP, CCT, and DM). Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 (mu)m. The corneas of men were thicker than those of women (P =0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects' CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P=0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P =0.04). The mean overall DM was -4.18 diopters. Men had less myopia than women (P< 0.001). Myopia was stable in the 20- to 40-year-old study population (P =0.089). A linear relationship was found between CCT and IOP (R(2) =0.152, P(less-than or equal to) 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found. Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.
M. Garcia-Medina. Department of Ophthalmology, Torrecardenas Hospital, Paraje de Torrecardenas s/n, 04009 Almeria, Spain. Email: manuelgarme@gmail.com
Classification:
8.1 Myopia (Part of: 8 Refractive errors in relation to glaucoma)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)