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Abstract #49162 Published in IGR 14-1
Imaging of the Iridocorneal Angle with the RTVue Spectral Domain Optical Coherence Tomography
Perera SA; Ho CL; Aung T; Baskaran M; Ho H; Tun TA; Lee TL; Kumar RSInvestigative Ophthalmology and Visual Science 2012; 53: 1710-1713
PURPOSE: To determine the ability of the RTVue spectral domain optical coherence tomography (SDOCT) to image the anterior chamber angle (ACA). METHODS: Consecutive subjects, recruited from glaucoma clinics, prospectively underwent ophthalmic evaluation including gonioscopy by an ophthalmologist and anterior chamber imaging with SDOCT, adapted with a corneal lens adapter (cornea anterior module-low magnification [CAM-L]) and anterior segment OCT (ASOCT), both performed by a technician. Two different ophthalmologists, masked to gonioscopy findings, assessed visualization of the scleral spur (SS), Schwalbe's line (SL), and trabecular meshwork (TM) by the two modalities. The ability to detect a closed angle was compared with gonioscopy. RESULTS: The average age (SD) of the 81 subjects enrolled was 64.1 (11.4) years; the majority were Chinese (91.4%) and female (61.7%). SDOCT images revealed the SS in 26.9% (56/324) of quadrants and the SL in 44.1% (143/324) of quadrants; in ASOCT images, the SS could be visualized in 69.1% (224/324) of quadrants (P < 0.0001), but the SL was undetectable. The TM was detected equally well (17.3%, P < 0.92) using either device. The angle status was gradable in only 41.7% images with SDOCT, compared with 71.3% of ASOCT images (P < 0.0001). ACA was classified as closed in 19.3% of quadrants (26/135) with SDOCT images and in 44.2% (102/231) with ASOCT images compared with 37.7% (122/324) on gonioscopy. When analyzing the horizontal quadrants only, both modalities agreed well with gonioscopy, 0.75 and 0.74, respectively (AC1 statistics). CONCLUSIONS: The RTVue SDOCT allowed visualization of SL, TM, and SS. However, these landmarks were not detected in a large percentage of images.
The Singapore National Eye Centre, Singapore and Singapore Eye Research Institute, Singapore.
Full articleClassification:
6.9.2.1 Anterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)