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Abstract #5762 Published in IGR 2-1
The ocular hypotensive effect of late pregnancy is higher in multigravidae than in primigravidae
Qureshi IA; Xi XR; Yaqob TGraefe's Archive for Clinical and Experimental Ophthalmology 2000; 238:64-67
BACKGROUND: Systemic hypertension and degenerative vascular disease are more common in multigravidae than in primigravidae. The present study investigated whether the known ocular hypotensive effect of late pregnancy is influenced by the number of pregnancies. METHODS: Intraocular pressure (IOP) was measured in normotensive third-trimester primigravidae and multigravidae along with nulligravida controls by means of the Goldmann applanation tonometer. Depending upon the number of previous pregnancies, multigravidae were divided into four subgroups. RESULTS: The IOP of the pregnant group (primigravidae and multigravidae together) was (mean±SEM) 2.1±0.07 mmHg (p < 0.001) lower than in the nulligravida control group. The IOP of nulligravidae was 1.7±0.06 mmHg (p < 0.001) and 2.5±0.01 mmHg (p < 0.001) higher than in third-trimester primigravidae and multigravidae, respectively. In all subgroups of multigravidae IOP was significantly lower (p < 0.02) than in primigravidae. The differences among different subgroups of multigravidae were statistically insignificant. CONCLUSION: Gravidity influences IOP and should be taken into account in future research.
Dr. I.A. Qureshi, Department of Biochemistry, Rawalpindi Medical College, Rawalpindi, Pakistan
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
