advertisement
Abstract #5872 Published in IGR 2-1
Wound healing modulation after glaucoma surgery
Cordeiro MF; Siriwardena D; Chang L; Khaw PTCurrent Opinions in Ophthalmology 2000; 11: 121-126
Recent developments in molecular and cell biology have made a major impact on our understanding of the wound healing process and its modification. In this article, the spectrum of therapies that are either currently available or have potential application as modulators of the scarring response following glaucoma surgery are reviewed. Refinement of existing antimetabolite regimens can improve surgical results, especially in carefully selected patient groups. However, the most promising new approach appears to be using molecular-based therapies, such as fully human neutralizing monoclonal antibodies, designed to target specific molecules in the scarring response. Such strategies ultimately offer the potential of safer, more specific, focal, and titratable treatment, with far-reaching clinical applications.
Dr. M.F. Cordeiro, Wound Healing Research/Glaucoma Units, Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
