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PURPOSE: To evaluate macular volume in normal and glaucomatous eyes using optical coherence tomography (OCT). METHODS: Fifty eyes of 30 patients (aged 49-68 years); 20 eyes normal, 15 eyes with early glaucoma, and 15 eyes with advanced glaucoma were studied with a commercially-available OCT unit (OCT 2000; Humphrey Zeiss, Dublin, CA). All eyes were examined at a scan length of 3.44 mm vertically across the fovea. OCT macular retinal thickness maps were used to calculate macular volume. RESULTS: The authors observed significant differences between groups. Normals (7.35 ± 0.455 mm3) and early glaucoma (7.09 ± 0.475 mm3), each had significantly greater volume than subjects with advanced glaucoma (6.678 ± 0.455 mm3). CONCLUSIONS: Volumetric analysis of macular thickness with OCT tomograms may be a useful method of documenting and monitoring patients with early glaucoma and advanced glaucoma. In the authors' analysis, and according to the observations of other authors, OCT macular volumes correlates significantly with glaucoma status.
A. Giovannini, MD, Institute of Ophthalmology, University of Ancona, Ancona, Italy
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.2 Optical coherence tomography (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)