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Abstract #46795 Published in IGR 13-3
Central corneal thickness in chinese subjects with primary angle closure glaucoma
Pang CE; Lee KY; Su DH; Htoon HM; Ng JY; Kumar RS; Aung TJournal of Glaucoma 2011;
PURPOSE: To characterize central corneal thickness (CCT) in Chinese eyes with primary angle closure glaucoma (PACG). METHODS: CCT was measured by ultrasound pachymetry in PACG eyes and compared with primary open-angle glaucoma (POAG) eyes. POAG eyes were further subdivided into high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) for analysis. PACG eyes had glaucomatous optic neuropathy and visual field loss, an angle in which at least 180 degrees of angle in which the posterior trabecular meshwork was not visible, and raised intraocular pressure (IOP) and/or peripheral anterior synechiae. Both HTG (IOP >21 mm Hg) and NTG (IOP consistently <21 mm Hg) eyes had glaucomatous optic neuropathy with compatible visual field defects and open angles. Further comparison was made with CCT data of 1067 normal subjects previously enrolled in a population-based study. RESULTS: We enrolled 154 patients with PACG and 300 with POAG. Mean age of PACG patients was 68.1(plus or minus)8.3 years compared with 71.1(plus or minus)12.4 years in POAG patients (P=0.002). There was no difference in mean CCT of PACG eyes (541.28(plus or minus)33.95 (mu)m) and POAG eyes (539.28(plus or minus)34.84 (mu)m, P=0.56) or normal eyes of control subjects (536.74(plus or minus)31.08 (mu)m) (P=0.07). However, mean CCT of NTG eyes (535.23(plus or minus)36.10 (mu)m) was significantly lower than that of HTG eyes (543.44(plus or minus)33.10 (mu)m, P=0.04), and HTG eyes had thicker CCT than normal eyes (P=0.01). CONCLUSIONS: PACG eyes had similar CCT as those with POAG or normal eyes in Chinese subjects.
C. E. Pang.
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)