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Abstract #28075 Published in IGR 13-1
Central corneal thickness and anterior scleral thickness in korean patients with open-angle glaucoma: An anterior segment optical coherence tomography study
Yoo C; Eom YS; Suh Y-W; Kim YYJournal of Glaucoma 2011; 20: 95-99
Purpose: To assess the correlation between central corneal thickness (CCT) and anterior scleral thickness (AST) in Korean patients with normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). Patients and Methods: Consecutive patients with POAG, NTG, and normal individuals were recruited. Anterior segment optical coherence tomography (AS-OCT, Visante) was used to measure CCT and AST. The AST was measured 2 mm posterior to the scleral spur in the temporal meridian. Statistical analysis of the data included ANOVA and Pearson correlation analysis. Results: One hundred and eight participants (36 with NTG, 35 with POAG, and 37 normal individuals) were enrolled. The CCT (NTG 514.81(plus or minus)25.03 (mu)m; POAG 534.43(plus or minus)34.79 (mu)m; controls 536.70(plus or minus)32.11 (mu)m) was found to be thinner in patients with NTG compared with POAG and the control eyes (P=0.023; P=0.009). The AST (NTG 738.53(plus or minus)53.63 (mu)m; POAG 771.86(plus or minus)53.75 (mu)m; controls 783.62(plus or minus)57.03 (mu)m) was thinner in the patients with NTG compared with POAG and the normal controls (P=0.032; P=0.002). No significant difference in AST was found among the POAG and control eyes (P=0.636). A correlation between CCT and AST was found only among the patients with NTG (r=0.469, P=0.004). However, no correlation was observed between CCT and AST in patients with POAG and controls. CONCLUSIONS: Anterior scleral thickness was correlated with CCT in the NTG group, but this correlation was not observed among the POAG or control groups.
Y. Y. Kim. Department of Ophthalmology, Korea University Guro Hospital, 97 Guro-dong-gil, Guro-gu, Seoul 152-703, South Korea. yongykim@mail.korea.ac.kr
Classification:
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
