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Abstract #13639 Published in IGR 8-2
Comparison of optical coherence tomography and fundus photography for measuring the optic disc size
Neubauer AS; Krieglstein TR; Chryssafis C; Thiel M; Kampik AOphthalmic and Physiological Optics 2006; 26: 13-18
PURPOSE: To assess the agreement and repeatability of optic nerve head (ONH) size measurements by optical coherence tomography (OCT) as compared to conventional planimetry of fundus photographs in normal eyes. METHODS: For comparison with planimetry the absolute size of the ONH of 25 eyes from 25 normal subjects were measured by both OCT and digital fundus photography (Zeiss FF camera 450). Repeatability of automated Stratus OCT measurements were investigated by repeatedly measuring the optic disc in five normal subjects. RESULTS: Mean disc size was 1763 ± 186 vertically and 1632 ± 160 μm horizontally on planimetry. On OCT, values of 1772 ± 317 μm vertically (p = 0.82) and a significantly smaller horizontal diameter of 1492 ± 302 μm (p = 0.04) were obtained. The 95% limits of agreement were (-546 μm; +527 μm) for vertical and (-502 μm; +782 μm) for horizontal planimetric compared to OCT measurements. In some cases large discrepancies existed. Repeatability of automatic measurements of the optic disc by OCT was moderately good with intra-class correlation coefficients (ICC) of 0.78 horizontally and 0.83 vertically. The coefficient of repeatability indicating instrument precision was 80 μm for horizontal and 168 μm for vertical measurements. CONCLUSIONS: OCT can be used to determine optic disc margins in moderate agreement with planimetry in normal subjects. However, in some cases significant disagreement with photographic assessment may occur making manual inspection advisable. Automatic disc detection by OCT is moderately repeatable.
Dr. T.R. Krieglstein, Department of Ophthalmology, Ludwig-Maximilians-Universität, Mathildenstr. 8, 80336 Munich, Germany
Classification:
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.9.2 Optical coherence tomography (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
