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Abstract #14254 Published in IGR 8-3
Changes in eyelid and cilia after switching from latanoprost to unoprostone
Izumi M; Inoue K; Wakakura M; Inouye J; Matsuo H; Hara T; Tomita GJapanese Journal of Clinical Ophthalmology 2006; 60: 837-841
Treatment with latanoprost induced eyelid pigmentation, hypertrichosis, elongation or thickening of cilia in 35 eyes of 21 patients with glaucoma or ocular hypertension. Latanoprost was switched to unoprostone in these patients. These complications were photographed before and 6 months after switching. The intraocular pressure (IOP) averaged 14.2 ± 2.2 mmHg before and 14.5 to 15.8 mmHg up to 6 months after switching. There was no significant change in IOP except at 2 months after switching. There was no difference in visual field defect before and 6 months after switching. Photographic evaluation showed improved eye-lid pigmentation in 29%, hypertrichosis in 42%, elongation in 44% and thickening of cilia in 44% of eyes. Questionnaire studies showed subjectively improved eyelid pigmentation in 71%, hypertrichosis in 92%, elongation in 44% and thickening of cilia in 44% of eyes. LA: Japanese
Dr. M. Izumi, Inouye Eye Hospital, 4-3 Kanda-Surugadai, Tokyo 101-0062, Japan
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
