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Top-Eight from the EGS Closed Meeting

September 5-7, 2003, Copenhagen, Denmark

Erik Greve

• A consensus on the definition of glaucoma is sadly lacking
• The New Danish Guidelines for the Diagnosis and Treatment of Primary Angle-Closure Glaucoma are out
• The nerve fiber layer symmetry test measured by OCT was reported to have an extremely good specificity-sensitivity ratio (97-100%), 38 eyes, MD 5-8 dB
• The visual field appears to change faster compared to rim area over time using a linear scale; the reverse was true of a logarithmic scale
• An automated outline of the ONH margin showed correspondence with a manual outline in 83%
• The definition of target IOP should include Quality of Life
• TGF-b activates both SMAD signaling cascade and MAPU signaling pathways, leading to increased expression of actin and fibronectin
• Modulation of MMPS is an exciting new modality for the prevention of scarring