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Top-Nine Asia Oceanic Glaucoma Society Meeting

October 19-21, 2001, Seoul, Korea

Gong J. Seong

  • In glaucoma, the correlation between disc topography and visual field damage in myopic-type discs differs from that in ordinary-shaped, non-myopic type discs.
  • Rho-associated protein kinase inhibitors have the potential to be developed into a treatment modality for glaucoma.
  • Low-dose administration of zinc can precondition low-grade stress in retinal ganglion cells to cope with future lethal insults.
  • Subjects with PACG had more advanced field loss than those with POAG, despite the short timespan since diagnosis. The superior hemifield was affected earlier in POAG: PACG showed no such difference. This significant difference in the pattern of field loss between the two disease has consequences for the pathophysiology of optic nerve damage.
  • Myocilin proteins and mRNA levels do not appear to correlate with age in normal human TM tissues. The levels of myocylin in OAG/OH specimens are not increased. These results argue against a direct role of myocylin, and reiterate the involvement of additonal factors in the pathogenesis of glaucoma.
  • GDx parameters were capable of differentiating glaucomatous from nonglaucomatous eyes, and the number equal to or greater than 26 was optimally 'outside normal limits' with respect to sensitivity. MD was significantly associated with global GDx parameters.
  • Unilateral visual field defects by conventional white-on-white perimetry may in fact underestimate structural as well as functional glaucomatous damage in contralateral eyes.
  • The stepwise treatment-medical management, intrableb autologous blood injection, additional sutures to the scleral flap, necrotic bleb excision and advancement of a formical conjunctival flap, was a useful method for managing hypotony after trabeculectomy with MMC.
  • ALPI was effective in eliminating residual appositional closure after iridotomy in eyes with plateau iris syndrome. The effect was maintained for years, and filtration surgery avoided in the long term.

Issue 3-3

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