advertisement

News Flashes IGR 8-2

OPTN mutations may cause glaucoma by a mechanism other than lowering thethreshold for apoptosis

Neurotrophin factor deprivation is unlikely to be the only signal triggering cell death after axotomy

The prediction of RGC density from perimetric sensitivity in humans was remarkably good

Repeatability of mfVEP was better than of standard automated perimetry

Ocular utilities diminish as vision in the better-seeing eye decreases

Androgen metabolism and androgen steroids may play a role in astrocyte responses to glaucomatous stimuli

The frequency of increased expression levels of endothelin B receptors is higher in glaucomatous optic nerves and the receptors were co-localized with reactive astrocyte processes

After trabeculectomy, 66% of patients showed increase of lens opacities over three years

Myocilin-induced glaucoma is a protein conformational disease, which results in TM cell death

CCT was not related to scleral thickness

The incidence of disc hemorrhages decreased after surgery

Non-responders to latanoprost were found in only 4.1%

OHT subjects with thinner corneas may either have early structural damage that has not yet manifested as characteristic optic nerve damage or visual field loss or they may represent a subset of patients who have an increased susceptibility to glaucomatous damage in the presence of high IOP and thin RNFL

The size of the somas and dendritic fields of surviving retinal ganglion cells have been enlarged as a result of glaucomatous damage to adjacent ganglion cells

In Singapore patients with unilateral acute primary angle closure, the risk of developing glaucoma in the fellow eye was 5.1% at a mean follow up of six years

CCT is somehow linked to glaucoma risk at a fundamental, biological level

It remains an open question whether a CCT-IOP nomogram should be used in individual patients

RNFL thinning is refractive error dependent

Cost-effectiveness data for treatment of patients with ocular hypertension provide important information for the management of glaucoma, provided assumptions on risk assessment in the individual patient are correct